Gastric Disorders - Causes and Treatments
Gastritis is the most common digestive disorder, which causes chronic stomach inflammation and in extreme cases may even lead to stomach ulcer. If you are frequently suffering from this avoidable agony, it's better to take it seriously to shun worsening of case.


What is Mastocytosis?

Mastocytosis (mas-toe-sigh-toe-sis) is one type of disorder wherein one has numerous mast cells in the body. A verity of blood cells situated in the skin, the linings of the stomach and intestine, and connective tissue (such as cartilage or tendons) are called mast cells. For survival mast cells are essential. These cells protect skin, stomach, and intestine from disease. Mast cells play a definite role in wound healing.

Mastocytosis happens irrespective of age. Among adults the effect of Mastocytosis is generally serious in nature. Mastocytosis also affects children mildly and they frequently grow faster. Initially E.

Nettleship and W. Tay described Mastocytosis. The British Medical Journal, 1869 Nettleship and Tay termed this as a “Rare form of Urticaria”. Paul Ehrlich identified Mast Cells in 1877. J.M. Ellis proved that Mastocytosis were present in the internal organs also in1949.

Types of Mastocytosis

Two of the kinds of Mastocytosis are: Cutaneous (skin) and systemic. Cutaneous and systemic forms are further sub-classified into various types. Urticaria pigmentosa is the most commonly known type of cutaneous variety. Urticaria pigmentosa occurs once mast cells are collected in the skin it is known as Urticaria pigmentosa. The scientific literature in 1933 was to report about the Urticaria pigmentosa.

The type of Mastocytosis appearing due to the growth of mast cells in the tissues is named Systemic Mastocytosis. The parts getting affected by this type of Mastocytosis are the organs such as the liver, spleen, bone marrow, and small intestine.

What are Mast Cells?

The cells that contribute mainly in fighting against infections are called Mast cells. They make chemical called histamine. Histamine, the chemical is made by mast cells is produced and leads to swelling, itching, and redness when your body is reacting to something. Mast cells are extensively present in the skin, the lungs and the intestines than in other parts of your body.

There are free cells that are located in the interstices of loose connective tissue. These vary in their abundance and are free to migrate through the extra cellular spaces. Among these wandering cells are the mast cells; these have a cell body filled with coarse granules that exhibit a characteristic meta-chromatic staining reaction. The function of these cells is not exactly understood, but they are known to produce and store in their granules two biologically active substances, histamine and heparin.

Mastocytosis Causes

Till date the proper cause of Mastocytosis is not established. This has lead to an embarrassing situation of not finding a way of treatment for this disorder.

What are the Symptoms of Mastocytosis?

Different persons show different symptoms of Mastocytosis. Symptoms differ with the location of additional mast cells. Mastocytosis in the skin has the symptoms as: red and itchy rash, hives, rash that looks like freckles, or a lump on your skin. Diarrhea and stomach pain are the symptoms present for Mastocytosis in the stomach and intestine. Some more symptoms, which are obvious: abdominal cramping, bone pain, abdominal discomfort, nausea and vomiting, ulcers, diarrhea, skin lesions, and episodes of hypotension or shock.

How does will the doctor detect Mastocytosis?

A skin biopsy, a bone marrow biopsy, a blood test or a urine test will help to detect the Mastocytosis.

Can Mastocytosis be treated?

Doctor can prescribe medication for the patient. Regrettably, it cannot be cured. The world is in search of proper reason and adequate treatment to this type of disorder.